By now, the COVID-19 pandemic is mostly an unpleasant memory in the minds of those old enough to remember it, except for those suffering from long COVID, those who lost loved ones or knew someone who died in it, or . . . well, maybe it's not just a memory after all. Whatever your personal experience of it was, there is no question that it was one of the biggest tragedies of the 21st century so far. And one of the more disturbing aspects of it is that we still don't know exactly how it started.
Some disasters can be traced down to the exact time and place of origin—for example, the Great Chicago Fire of of 1871, which began around 8:30 PM on October 8 in or around a barn at 137 W. DeKoven Street. It is agreed by all interested parties that the COVID pandemic originated in the city of Wuhan, but beyond that the story gets cloudy.
Soon after the virus spread worldwide, two main theories of its origin emerged. One, heavily promoted by the government of China, asserted that it was a zoonotic disease which jumped from its original host animal to people after undergoing mutations making it able to infect humans. As Wuhan hosted extensive live-animal food markets, this theory was plausible. The other theory was that experiments or research at the Wuhan Institute of Virology had led to a lab leak of a deliberately enhanced virus.
Despite some co-operation from the Wuhan authorities in an investigation by the World Health Organization in early 2021, no definitive evidence has ever emerged that allows a Chicago-Fire-style reconstruction of exactly how the virus got its start in human beings. And it's possible that no such evidence may exist, or if it still exists, it may never be found.
The Summer 2026 issue of The New Atlantis carries some additional circumstantial evidence that may form important pieces of the puzzle if it is ever solved. Dan Silver spent the years 2003 to 2023 as a "rapporteur" (basically, an investigator charged by an official body to do a specific investigation) with the international Program for Monitoring Emerging Diseases. So his full-time job was to look into the origins of SARS, COVID, and similar epidemics, and he learned a lot about obscure sources of information in his work.
One of those obscure sources concerns the waste-disposal facilities in and around Wuhan that the Wuhan Center for Disease Control and Prevention (CDC) and the separate Wuhan Institute of Virology used to dispose of biological hazardous waste. Normally there were three such facilities. But Silver has found in public records that in May of 2019, two of the three facilities that normally processed hazardous waste from both organizations were disabled and shut down by fires. That left only one operational, and it was 190 miles away.
In addition, the Wuhan CDC admits publicly that for twenty-five years, it had been accumulating waste products on site, in violation of a Chinese law that says no hazardous waste may be stored for more than a year after it is created. By the winter of 2019, all this waste had been cleared away in a move to a new facility in Wuhan.
Putting the pieces together, Silver says that by implication, twenty-five years' worth of possibly biological hazardous waste was moved 190 miles from Wuhan to the one remaining hazardous-waste facility some time between the summer and winter of 2019, when the Wuhan CDC completed its move to its new facility. And it was in the fall of 2019 that the earliest cases of what came to be known as COVID-19 appeared.
While not exactly a smoking gun, these facts at a minimum indicate that the general level of caution regarding such waste was way below what was warranted by the potentially dangerous materials being handled. A third variation of the two theories mentioned above is the following.
While the Wuhan Institute of Virology was developing "gain-of-function" virus materials (not necessarily complete viruses), they were also famous for collecting viruses in the wild under less than safe conditions. It's entirely possible that while no engineered virus escaped the lab, some piece of material from their wide-ranging investigations of bat viruses from different regions of China was carelessly disposed of, possibly because of the waste-material disruptions that began the previous summer. And that material might have been the first to infect a human being with COVID.
This third possibility combines features of the first two. It allows the virus to have originated by natural and not engineered means, but it also places one of the Wuhan organizations (either the CDC or more likely the Institute of Virology, which performed the collecting) at the center of the process, as a concentrator of naturally hazardous material in a populous area.
Again, unless more new data is unearthed by diligent investigators such as Silver, the world may never know the precise way that the COVID-19 virus began its world tour of death and destruction. Silver reports that China has significantly tightened its enforcement of regulations regarding biological waste and hazards since then, which is a good thing. Nobody wants a repeat of the COVID epidemic, least of all China, which suffered an extent of damage that is still being revealed.
While we may never know how the virus first spread to humans, we know how to prevent such spread of potentially dangerous viruses in terms of good laboratory techniques and institutional discipline. Countless disasters of all kinds are caused by what can only be termed sloppiness, whether by an individual or an organization. When researchers deal with dangerous stuff, they are honor-bound to take all reasonable precautions to protect themselves and the society hosting them. This doesn't always happen, and human carelessness may in fact be a significant cause of the COVID pandemic. Regardless of the exact origin, the experience is a constant reminder that little mistakes in certain critical activities can have literally worldwide consequences.
Sources: Dan Silver's article "A New Piece of the Puzzle of Covid's Origin" appeared on pp. 67-72 of the Summer 2026 issue of The New Atlantis. I also referred to an editorial by Jin-Hong Yoo of the College of Medicine of the Catholic University of Korea at https://pmc.ncbi.nlm.nih.gov/articles/PMC12040609/.